S1 Fig. Pedigrees having segregating number 1 focal excessive sweating Variants were annotated using AN Mar 22 with RefSeq and Ensembl, Combined Annotation Dependent Depletion (CADD) scores , allele frequencies and dbNSFP (v3.0) annotations . For rare variant analysis, we filtered out common variants from the European population. Therefore, we selected variants with a minor [...]